For specific measurement and quantification of cell death.
M30 Apoptosense® ELISA
Product no. 10011
The M30 Apoptosense® ELISA assay is based on the unique M30® antibody that recognizes a neo-epitope of keratin 18 (K18), formed after caspase cleavage during apoptosis. The M30 Apoptosense® ELISA is CE marked as a medical device for in vitro diagnostic use.
The M30 CytoDeath™ ELISA offers a unique possibility to measure human cell death by apoptosis in cell cultures, multicellular spheroids and organ culture systems. The M30 CytoDeath™ ELISA is a product developed for cell culture applications, with a dynamic range and sensitivity suitable for in vitro work, making it a useful drug screening tool.
The assay, based on the M5 and the M6 antibodies, measures total cell death due to apoptosis or necrosis and is intended for human serum or plasma. The assay is CE marked as a medical device for in vitro diagnostic use. The M65® ELISA measures total cell death due to apoptosis or necrosis by quantifying the levels of total soluble keratin 18 (K18) released from dying epithelial cells.
The M65 EpiDeath® ELISA measures the concentration of total soluble keratin 18 (K18) in human plasma, serum and cell culture supernatants. The K18 levels reflect the amount of total cell death, due to apoptosis or necrosis of epithelial cells.
The M65 EpiRat™ ELISA is based on the M5 and M6 antibodies, which bind to the biomarker Keratin-18 (K18). K18 is an intermediate filament protein in epithelial cells. The concentration of K18 reflects the amount of overall cell death, both apoptosis and necrosis, in K18 positive cells. Levels of K18 are commonly elevated when the liver endures damage, through disease or toxicological effects.